Cells have an inherent defense mechanism—the innate immune system—that safeguards them against encroaching pathogens like bacteria and viruses. Researchers in past investigations have delineated the cytoplasmic cGAS-STING pathway, notable for its role in detecting foreign nucleic acids, specifically double-stranded DNA. This pathway, operating within the cell’s cytoplasm, plays a vital part in orchestrating responses to potential threats, contributing significantly to the cell’s ability to fend off harmful invaders. By comprehensively understanding this intricate system, scientists aim to unravel further insights into cellular defense mechanisms, potentially paving the way for innovative strategies in combating infectious agents that pose risks to human health and well-being.
Micronuclei not primary activator of cGAS/STING pathway, scientists discover
